CellKey™ Technology FAQ

What is Cellular Dielectric Spectroscopy (CDS)?

Cellular dielectric spectroscopy (CDS) is a revolutionary, impedance-based technology for drug discovery. It has been initially applied to pharmacological assessment of cell surface receptor activity.

Does CDS affect the cells?

No. Cellular dielectric spectroscopy is a non-invasive methodology and is harmless to the cells.

What is the CellKey™ System?

The CellKey™ System is a label-free, cell-based assay platform based on cellular dielectric spectroscopy technology.

What does the CellKey™ System measure?

The CellKey™ System is used to measure complex impedance changes: delta Z or dZ. Impedance (Z) is the ratio of voltage to current as described by Ohm's law (Z = V/I).

What plate formats are compatible with the CellKey™ System?

The CellKey™ System operates in a 96-well mode and the CellKey™384 System operates in a 384-well mode.

What is the size of each instrument?

The CellKey™ System instrument is 70 cm/28 in. high, 85 cm/33 in. wide, and 58 cm/23 in. deep.
The CellKey™384 System instrument is 70 cm/28 in. high, 100 cm/39 in. wide, and 58 cm/23 in. deep.

How large are the raw data files?

For a 10-minute assay on the CellKey™ System, the data files are approximately 10 Mb.
For a 10-minute assay on the CellKey™384 System, the data files are approximately 15 Mb.

Do I have to use specific types of consumables with the CellKey™ System?

Yes. Cells must be seeded onto custom microplates that contain electrodes at the bottom of each well. There are two choices of microplates for the CellKey™ System: a Standard 96W microplate (CellKey™ Standard 96W microplate, PN 1019176) and a Small Sample microplate (CellKey™ Small Sample 96W microplate, PN 1026496). The CellKey™384 System requires the CellKey™ Standard 384W microplate, and the custom CellKey™384 Pipette Tips.

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